Investor Presentaiton

Screening Early Disease Detection Minimal Residual Disease Recurrence Detection & Surveillance Therapy Selection Advanced Cancer Care >120M Average-Risk Individuals >15M Early-Stage Patients and Survivors Cancer Detection Surgery +/- Adjuvant 1 Do I have cancer? 2 Do I still have cancer? GUARDANT™ >700K Advanced Cancer Patients INVESTOR 20 DAY 23 Recurrence 1st Line Tx 2nd Line Tx +TX 2 Has my cancer returned? 5 3 Am I responding to therapy? 4 What kind of therapy is best for me? What kind of cancer do I have? Where is my cancer? How is my immune system responding? 39 39

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