Connecting Innovation to Purpose

31 CB1 contribution to "Diabesity” is well understood Hepatic tissue Lipogenesis Glucose production Insulin signaling Fatty acid oxidation Obesity Skeletal tissue Insulin resistance Diabetes mellitus ↑ CBIR ↑ Neuronal tissue Neuropeptide ↑ Appetite Lipogenesis Body weight Obesity Diabesity Pancreatic cells Insulin secretion Diabetes mellitus Adipose tissue Lipogenesis Adipogenesis Inflammation Adiponectin secretion Obesity Source(s): Targeting the endocannabinoid system in diabesity: Fact or fiction?, Drug Discovery Today, Deeba et al. Mar 2021.

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