RSV Seasonal Vaccine Introduction and Growth Strategy slide image

RSV Seasonal Vaccine Introduction and Growth Strategy

68 potential new vaccines and medicines in pipeline Phase II -19 assets Infectious diseases HIV (VIIV) Respiratory/Immunology Oncology Opportunity driven 3437949 4406371 3536852 3528869 4023393 4178116 5101956 5101955 4106647 4348413 3036656 sanfetrinem cilexetil (GV118819) BVL-GSK098 VIR-2482 3810109 Benlysta (belimumab) 3858279 belrestotug (4428859) 4532990 Recombinant protein, adjuvanted* Live, attenuated GMMA* Viral vector with recombinant protein, adjuvanted* Recombinant protein, OMV, conjugated vaccine Live, attenuated MAPS* MAPS* Recombinant protein, adjuvanted* GMMA Leucyl t-RNA synthetase inhibitor* Serine beta lactamase inhibitor* Ethionamide booster* Neutralizing monoclonal antibody*5 Broadly neutralizing antibody* Anti-BLys antibody Anti-CCL17 antibody* Anti-TIGIT antibody* HSD17B13 siRNA* Shigella Malaria fractional dose MMRV new strain Therapeutic hepatitis B virus¹** MenABCWY, 2nd Gen Varicella new strain Adult pneumococcal disease, 24-valent Paediatric pneumococcal disease, 24-valent Human papillomavirus Gonorrhea¹ Tuberculosis Tuberculosis Tuberculosis Influenza HIV Systemic sclerosis associated interstitial lung disease Osteoarthritis pain**7 Non-small cell lung cancer Non-alcoholic steatohepatitis GSK *In-license or other alliance relationship with third party ** Additional indications or candidates also under investigation In registration 1. In phase I/II study 2. Transition activities underway to enable further progression by partner 3. GSK has an exclusive global license option to co-develop and commercialise the candidate 4. Imminent study start 5. GSK has exclusive option to co-develop post phase II 6. Phase II/III study start expected in 2023 7. Phase II study start expected in 2023 8. Approved in US and EU 9. Phase III study start expected in 2023 10. Phase III trial in patients with progranulin gene mutation 38
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