Q3 2022 Results slide image

Q3 2022 Results

Company overview Financial review 2022 priorities Appendix References Entresto® +31% cc, growing strongly across geographies Sales evolution USD m, % cc US weekly TRX¹ Total prescriptions (000) Ex-US US 100 90 +31% 80 1,135 70 924 60 565 50 519 40 30 20 570 405 10 0 Q3 2021 Q3 2022 10/07/2015 прициу 23/09/2022 1 GROWTH C Entresto AZ K &K L Strong quarter performance ■ WW: Increased to >8m patients on treatment? ■ US: Accelerated momentum, ~1.1m TRx in Q3 Europe: Strong demand growth continues Future growth drivers ☐ Only 1/3 of eligible HFrEF population on treatment in G72 Strong profile in clinical and RW settings in HF3,4 Guidelines (AHA/ACC/HFSA) support Entresto as 1st choice in HFrEF, expand support in HFPEF5,6 Hypertension: High unmet need in Asia Pacific See last page for references TRX Total Prescriptions WW-Worldwide HFrEF - heart failure with reduced ejection fraction HFSA Heart Failure Society of America HFPEF-heart failure with preserved ejection fraction RW - Real world AHA-American Heart Association ACC American College of Cardiology 8 Investor Relations | Q3 2022 Results ✓ NOVARTIS | Reimagining Medicine
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