Investor Presentaiton

BND-35 is an antagonist antibody that blocks ILT3 BND-35 promotes an inflammatory TME Suppressive tumor microenvironment Decreases activity of suppressive myeloid cells Increases effector T cell activity Inflammatory tumor microenvironment Tumor Pro-tumorigenic signals ILT3 Inhibitory Signal BND-35 Tumor Anti-tumor activity BND-35 BIOND BIOLOGICS Suppressive myeloid cells Suppressed T cell Activated myeloid cells Biond Biologics Corporate Presentation | May 2021 | Non-confidential ILT3 Activated T cell 27 27

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