3Q22 Investor Update

1. 2. 3. HEMP/CANNABIS REVENUE & PROFIT BREAKDOWN Unit sales¹ Net revenue Gross profit ■ 3Q 2022 23,719 $7.8M $(17K) ■ Hemp/Cannabis 3Q 2021² 12,996 $6.3M $697K Net revenue growth QoQ primarily driven by: ■ Addition of GVB contribution Significant GVB organic revenue volume growth QoQ Q3 2022 pro forma gross margin was approximately 8.1% compared with 9.7% prior year. Change % 83% 25% NM³ Additional hemp/cannabis opportunity driven by: Ž 22ND CENTURY GROUP ▪ Organic growth reflecting continued strong customer demand Hemp/cannabis unit sales volume is measured as kilograms. GVB acquisition occurred on May 13, 2022. All prior period results are provided for illustrative purposes only. These pro forma results do not purport to be indicative of the results that would have been obtained, or to be a projection of results that may be obtained in the futures. Refer to Q3 2022 Form 10-Q Note 2 of the Condensed Consolidated Financial Statements for description of pro forma adjustments as required under U.S. GAAP. Not meaningful; the percentage change is determined to be not meaningful to the analysis provided Increased profit margin from vertical integration with new Prineville crude extraction facility becoming fully operational 20

View entire presentation