Ginkgo Investor Conference Presentation Deck
We believe our methanol-free Pichia pastoris protein engineering system is
significantly better than best-in-class comparables
100,000+ synthetic expression systems
with tunable strength and regulatory
characteristics, best of which are 20x
stronger than AOX1 with Methanol
Ginkgo Pichia Promoters vs Best In Class
Ginkgo's synthetic promoters were 5-20X stronger than best-in-class
Fold improvement over BIC promoter
20
15
10
5
0
Best In Class
10,000
Promoter Strength
100
1
5x
Ginkgo Synthetic
Promoter 1
15x
Ginkgo Synthetic
Promoter 2
Best in class
expression
system
100
Leakiness
20x
Ginkgo Synthetic
Promoter 3
10,000
>20g/L intracellular
protein production
High-performance
methanol and
methanol-free options
NRE
20
ā Intracellular Titer (g/L)
Prototype
MVP 1
Methanol-based
(fluorescent protein)
MVP 2
Commercial strain
Methanol-free
Fully validated high-performance fermentation
processes, scalable from AMBR 250 to 10,000L+
14
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J.P. MORGAN HEALTHCARE CONFERENCE 2022View entire presentation