Q1 2023 Earnings Presentation

APPENDIX Q1 2023 Reconciliation of GAAP and Non-GAAP Results Year-over-Year [$M] GAAP Operating Income Restructuring Costs Acquisition-Related Costs Purchased Intangible Amortization Other Costs TOTAL Non-GAAP Operating Income Non-GAAP Interest & Other Expense, net Non-GAAP Profit Before Tax Non-GAAP Income Tax Provision Non-GAAP Tax Rate Minority Interest Non-GAAP Net Income* *Attributable to Bruker. Sum of items may not total due to rounding. 2023 Bruker Q1 2023 122.7 0.5 3.0 10.7 2.5 16.7 139.4 (6.5) 132.9 (36.9) 27.8% (0.9) 95.1 Q1 2022 96.5 0.4 5.3 9.3 4.3 19.3 115.8 (4.2) 111.6 (36.5) 32.7% (0.5) 74.6 Q1 2023 Earnings Presentation | BRUKER May 4, 2023 I 19

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