OmniAb Results Presentation Deck

Ion Channels and Transporters • lon channels are key components in a wide variety of biological processes that involve rapid changes in cells Present in all human cells and affect vital functions such as nerve transmission, muscle contraction, cellular secretory processes and fluid movement Have broad therapeutic applicability including neurologic and metabolic diseases, pain, cancers, infectious diseases, and many others Inside of cell Source: Ion Channels, Guide to Pharmacology lons Closed Ion Channel Open Ion Channel lons In the search for novel drugs, ion channels are viewed as high-value targets 11 Outside of cell Cell Membrane OmniAb

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