Avantor Results Presentation Deck

2 Core Organic Growth & Adjusted EBITDA (Annual) USD in millions Navantor™ Total Avantor, Global GAAP consolidated net sales Core organic growth (decline) COVID Impact Organic growth (decline) M&A Impact FX Impact Reported net sales growth (decline) GAAP gross profit Adjustments for Ritter & Masterflex¹ Adjusted gross profit (non-GAAP) GAAP SG&A expense Amortization Acquisition/Integration-related expenses 2,3 Purchase accounting adjustments* Other stock-based compensation (expense) benefit Restructuring & severance charges5 Reserve for certain legal matters Impairment charges' Adjusted SG&A expense (non-GAAP) Other reconciliation items Depreciation Loss on extinguishment of debt Net foreign currency loss (gain) from financing activities Receipt of disgorgement penalty Total other adjustments Adjusted EBITDA (non-GAAP) FY2020 $6,394 $ $71 266 $337 17 $353 FY2020 $ $2,080 $2,080 $1,036 88 347 $1,374 21.5% (307) (17) -4.8% -0.3% 0.0% 0.0% (1) (12) -0.2% 0.0% 0.0% 16.2% (1) % 1.2% 4.4% 5.6% 0.0% 0.2% 5.8% $434 $1,142 % 32.5% 0.0% 32.5% 1.4% 5.4% 0.0% 0.0% 6.8% 17.9% FY2021 $7,386 $ $582 138 $719 143 130 $993 FY2021 $ $2,503 33.9% (6) -0.1% $2,509 33.9% $1,531 (291) (94) % 9.1% 2.2% 11.3% 2.2% 2.0% 15.5% (3) (5) 88 12 1 (13) $89 % -1.3% 0.0% 0.0% -0.1% 0.0% 0.0% $1,138 15.4% $1,459 20.7% -3.9% 1.2% 0.2% 0.0% -0.2% 1.2% 19.7% FY2022 $7,512 $ $441 (266) $175 268 (317) $126 FY2022 $ % $2,603 34.6% (14) -0.2% $2,617 34.8% $1,473 (318) (19) 4 3 (4) $1,140 % 6.0% -3.6% 2.4% 3.6% -4.3% 1.7% 87 13 7 $107 19.6% -4.2% -0.2% 0.1% 0.0% 0.0% 0.0% 0.0% 15.2% 1.2% 0.2% 0.1% 0.0% 1.4% $1,571 20.9% FY2023 YTD $5,244 $ % ($306) -5.3% (175) ($481) -3.1% -8.4% 0.0% 0.1% -8.3% 8 ($473) FY2023 YTD % $ $1,793 $1,793 $1,280 (233) (8) (0) (18) (4) (161) $856 69 6 (2) $73 $1,007 34.2% 0.0% 34.2% 24.4% -4.4% -0.2% 0.0% 0.0% -0.3% -0.1% -3.1% 16.3% 1.3% 0.1% 0.0% 0.0% 1.4% 19.2% 5

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