Creating a Leader in Blood-Based MultiCancer Screening

Screen Fewer People to Detect 1 Cancer with Multi-Cancer Approach Problem #1 Cancer is leading cause of death in people under 85 in U.S. 90% ~9/10 people can survive if it's caught at an early stage EXACT SCIENCES Thrive. Earlier Detection Solution 166 People need to be screened to detect 1 colorectal cancer ~30 People need to be screened to detect 1 type of multiple cancers Sources: Centers for Disease Control and Prevention; U.S. Census Bureau; Imperiale TF et al., N Engl J Med (2014); Karwinski 1990, Burton 1998, Sens 2009, Ahlquist 2017; Assumes -85% sensitivity for a multi-cancer test Market 114M People between ages 50 and 85 in the U.S. who could be screened 5

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