Company Overview

For personal use only 28 Projects over which proof of concept has been established in either pre-clinical, phase 1 or phase 2 clinical studies. Established drug formulations with data packages necessary for regulatory applications. Proof of concept data from pre-clinical and clinical studies supporting the proposed therapeutic applications. Regulatory filings for multiple drug products. Granted and pending patents for manufacturing methods, drug formulations and methods of use to treat a range of conditions. Covers the entire drug development process from raw materials to patient dosing. Different cannabinoid development strategy than IHL's current programs. - Recently completed acquisition of APIRX adds unique cannabinoid formulations and delivery mechanisms protected by patent. Incannex Clinical Project IHL-42X Obstructive Sleep Apnoea IHL-675A Inflammatory Lung Disease IHL-675A Rheumatoid Arthritis IHL-675A Inflammatory Bowel Disease IHL-216A TBI/Concussion Psi-GAD Generalized Anxiety Disorder MedChew™-1401 Pain and Spasticity in Multiple Sclerosis MedChew™M GB Post-herpatic Neuralgia MedChew™-1502 Parkinson's Disease MedChewTM-1503 Dementia MedChew™ RL Restless Legs Syndrome MedChew™ Dronabinol Nausea and Vomiting in Chemotherapy APIRX 1505 Flotex Gastro: Chrohn's Disease Addressable Market Opportunity (in US$) $10.4B (U.S.) $50.4B (U.S.) by 2022 $57B (U.S.) by 2022 $20B (U.S.) by 2021 $2.9B in 2019 8M people (U.S. & AUS) $62B (Global) in '21 (a) $3.7B (U.S.) by '27 (n) $8.05B (Global) by '27; 6.5% CAGR (1) $23.9B (Global) by '28; 7.9% CAGR (m) 12.1.% prevalence of U.S. pop. (1) $3.1B (Global) by '24 (e) $12.6B (Global) by '24 (k) (a) Frost & Sullivan Market Report as commissioned by APIRX, Sept. 2021 (d) Frost & Sullivan Market Report as commissioned by APIRX, Sept. 2021, market opportunity is Irritable Bowel Syndrome / Disease (e) Healdkeepers, "Chemotherapy Induced Nausea and vomiting (CINV) Drugs Market Research Report, History and Forecast 2022-2027", Jan. 2, 2022 () Straits Research: Home Care Sleep Screening Devices Market Stage of Development Phase 2A completed Pre-clinical completed Pre-clinical completed Pre-clinical completed Pre-clinical completed Phase 2A ongoing Pre-clinical Pre-clinical Pre-clinical Pre-clinical Pre-clinical Phase 1A completed Pre-clinical Regulatory Stage of Development FDA Pre-IND completed FDA Pre-IND completed FDA Pre-IND scheduled (Sept. 2022) FDA Pre-IND completed Pre-IND completed in NL and Switzerland FDA Pre-IND FDA Pre-IND FDA Pre-IND FDA Pre-IND FDA Pre-IND completed Pre-regulatory Next Steps IND opening study Phase 1 CT Phase 1 CT Phase 1 CT IND opening study Phase 1 Phase 1 Phase 1 Phase 1 Phase 1 Phase 1 Phase 1B Phase 1 (1) Global Market Insights, "Parkinson's Disease Therapeutics Market", Base Year 2020 (m) Accurize Market Research, "Dementia Drugs Treatment Market", Nov. 27, 2021 (n) Comserve,"U.S. Shingles Vaccine Market", Jan. 4, 2022 (r) Coherent Market Insights "Inflammatory Bowel Disease Market Analysis", Sept. 2021. Relevant Patents Investor Presentation 1x Pending Deemed novel & inventive 2x Pending Deemed novel & inventive 2x Pending Deemed novel & inventive 2x Pending Deemed novel & inventive 2x Pending Deemed novel & inventive Drafting Granted Granted Granted Granted Granted Granted (k) Heraldkeepers, "Crohn's Disease Drugs Market Research Report 2022: Prospects, Trends Analysis, Market Size and Forecasts to 2027", Jan. 2, 2022 Drafting 7

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