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Investor Presentation

New and Emerging Markets 2020 Revenue: % of 2020 Revenue: 2021e Revenue: 2021e Incremental: % of 2021 Revenue: Franchise Tailwinds: Where our Products Play: Healthy Biologics Pipeline to Fuel Future Growth: mAbs¹ COVID-19 Vaccines & Therapeutics $46M 13% $175 - $180M (from $46M in 2020) $129 - $134M ~27% Filtration, Chromatography, Proteins Viral vector vaccines rProteins mRNA >120 FDA approved YE 2020 >630 clinical trials Therapeutic mAbs 3 FDA EUA approved YE 2020 >1,500 clinical trials 1. Antibodies to Watch in 2020; MAbs. 2020 Jan-Dec; 12(1): 170353 2. Alliance for Regenerative Medicine Q3 2020 report https://alliancerm.org/sector-report/q3-2020-trend-talk/Deloitte report with references GT CAGR Gene and Cell Therapy R REPLIGEN INSPIRING ADVANCES IN BIOPROCESSING $54M 15% (+30% year-on-year growth) $71 - $76M (+30% -40% year-on year growth) $16 - $22M ~11% Filtration, Chromatography, Process Analytics Plasmids AAV Lentivirus mRNA 9 FDA approved YE 2020 >1,000 clinical trials² 8
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