Genelux Investor Presentation Deck
Demonstrated Deep and Durable Tumor Shrinkage
Tumor Shrinkage
Key Clinical Takeaways
Refractory patients
performed as well as resistant
patients
Tumor Shrinkage
Overall, 86% of PRROC patients
showed tumor reduction, with
91% of Platinum-refractory
patients showing tumor reduction
ā
Four patients had 100% reduction
target lesions (two with
confirmed CR), including two
platinum-refractory patients
Duration of Response (DOR)
DOR of 7.6 Months in all platinum-
ā
Resistant patients
DOR of 8.0 Months in platinum-
refractory patients
GENELUX
Change of target lesion size (%
change of SLD)
Best change of target lesions from
baseline (%)
100
80
60
40
20
60
40
20
-20
-40
-20
-40 -30% partial response
-60
-80
-100
-60
-80
15A-18
-100
15B-09
158-19
15A-19
15A-27
E-POS
120
platinum-resistant
platinum-refractory
15B-18
15A-06
15A-30
180
SA-2
158-01
15A-29
240
Duration of Response
Baseline tumor burden as Sum of Longest Diameter of target lesions (mm)
15A-05
Time (days)
300
15A-37
158-17
360
15A-22
15A-16
SA-0
PD
OR (CR or PR)
SD
420
15A-25
480
158-15
15A-31
SA-3
540
-30% partial response
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