Omega Therapeutics IPO Presentation Deck slide image

Omega Therapeutics IPO Presentation Deck

Omega's platform has the potential to be an unprecedented and pioneering approach to high-value transformative therapies in pursuit of high-value targets Focus "table-stakes" of most gene- based therapies Select Monogenic Diseases Precisely correct genetic or epigenetic dysregulation in monogenic rare and non-rare diseases (e.g., alopecia, Hypercholesterolemia, Fragile X, FA) ©2021 Omega Therapeutics, Inc. Omega's transformative value creation Regenerative Medicine Recapitulate developmental and mature-state gene expression to drive cellular regeneration and restore normal function (e.g., Liver, Pancreas, Heart, Cornea regen., T cell prog.) Multigenic Diseases Including Immunology Precisely up- or down-regulate single or multiple genes within an IGD or across IGDs (e.g., ARDS (Covid19), RA, IBD, Obesity, CHF, IPF) Oncology Precisely regulate target oncogenes including historically challenging or un-druggable targets in various cancers (e.g., HCC, NSCLC, Pancreatic cancer. GBM) Source: Evaluate pharma, market research reports, internal analysis Market potential $25B+ $ 150B+ $100B+ 14
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