Akouos IPO Presentation Deck

Novel, Minimally Invasive Delivery Approach Designed to Enable Efficient Access to Target Cells and Controlled Distribution of Product Candidates Throughout the Cochlea 15 0.00 8 0 Oval Window Round Window Membrane (RWM) Akouos Device in RWM CONFIDENTIAL 20 Uncoiled Cochlea Oval Window Base Injected fluid path Designed to allow for the safe and effective delivery of product candidates through the RWM Minimally invasive device delivers product candidates in a fixed volume and at a controlled flow rate • Design allows for distribution of product candidates across the full length of the cochlea AKOUOS Apex 1 8.0 2.0 0.5 Frequency Distribution Along the Cochlea 0.02 kHz

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