Kymera Results Presentation Deck
Mean % Change in Pain
(+/- S.E. of Mean)
0
-10
-20
-30
-40
-50
-60
-70
-80
KYMERA
0
Mean % Change in Worst
Pain Over Past Week
-17.5 I
7
-14.6
-36
14
Pain NRS: Mean 49 to 55% Reduction
Pain NRS30: 50 to 60% Response Rate
All HS (N=12)*
-31.2
-47.5
-40
21
Day
-55.2
28
-46
Ⓒ2022 KYMERA THERAPEUTICS, INC.
-43.5
-48.8
-49.3 -52.2
35
Moderate to Severe (N=10)
42
*One patient is censored for Day 35 and Day 42 since the patient started on ustekinumab, steroids and abx on Day 34.
% of Pain NRS30 Responders
(80% CI)
% of Patients with ≥30% and ≥1 Unit Reduction
in Worst Skin Pain Over the Past Week
100
90
80
70
60
50
40
30
20
10
O
0
20
7
17
50
14
42
70
All HS patients (N=12)
58
21
Day
60
50
28
60
35
50
60
50
42
Moderate to Severe (N=10)
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