Ocuphire Pharma Investor Day Presentation Deck

RM 43 Problem: Dilated Eyes for Exams and Procedures Patients Report Significant Side Effects after Dilated Eye Exam The Problem Pharmacologically-induced pupil dilation is a necessary tool for routine ophthalmoscopy... ...but there is 6 to 24 hours of impaired vision including: Inability to Focus ● ● Photophobia (sensitivity to light) Cycloplegia (loss of accommodation) Difficulty Reading and Driving Halos and Glare 1. GlobalData Market Research Survey; Oraverse and Regitine Label Physician's Use of Mydriatic Agents¹ Cyclopentolate 5% Paremyd 9% Phenylephrine Alone 16% Tropicamide and Phenylephrine 18% Tropicamide Alone 52% Note - Tropicamide and Cyclopentolate have same MOA NO REVERSAL DROPS COMMERCIALLY AVAILABLE Ocuphire PHARMA

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