Avantor Investor Presentation Deck

Q1 adjusted P&L USD in millions Reported Revenue Core organic growth Adj. Gross Profit Adj. Gross Profit % Adj. EBITDA Adj. EBITDA % Adj. Earnings Per Share Free Cash Flow Adj. Net Leverage Navantor™ Q1'23 $1,780.3 -1.8% $624.8 35.1% $346.2 19.4% $0.29 $191.5 3.8X3 Q1'22 $1,950.4 7.3% $689.9 35.4% $423.1 21.7% $0.38 $127.7 4.0X³ T COMMENTS Low single-digit core organic growth of bioproduction and >20% growth in biomaterials Inventory destocking in line with expectations Continued momentum in commercial excellence Roll off of high margin COVID-19 revenues and inventory destocking Active pipeline of productivity initiatives SG&A increase driven by wage inflation and growth investments Interest and tax expense in line with expectations COVID-19, FX¹ and interest expense represented ~$0.06 headwind to adj. EPS FCF conversion of ~100% in Q1 2023² Positive impact from working capital initiatives >$200M of debt paydown in Q1 Within target leverage of 2X - 4X Note: Core organic growth is organic growth net of COVID-19 impact. 1. Represents foreign exchange translation exposure, primarily from European business (~35% of sales). 2. Conversion: Free Cash Flow / Adj. Net Income. 3. Represents Adj. Net Leverage as of March 31, 2023 and March 31, 2022, respectively. 4

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