Kymera Investor Day Presentation Deck slide image

Kymera Investor Day Presentation Deck

● ● ● ● ● ● Expanding the Druggable Proteome with TPD Kymera intends to drug all target classes using targeted protein degradation A comprehensive hit finding toolbox with key Al and machine learning inputs has been developed to identify ligands against novel E3 and undrugged targets Our capabilities have evolved to accurately predict human active doses and compound properties We have developed know-how and technologies to drug inadequately drugged targets such as IRAK4 and MDM2, undrugged targets such as STAT3 and have for the first time in TPD drugged targets in a tissue selective manner using our E3 ligase toolbox. Kymera has established a new discovery unit to identify new molecular glue degrader drugs focused on undrugged/un-ligandable high value protein targets Multiple strategic collaborations have been established to enable MG Discovery KYMERA ©2021 KYMERA THERAPEUTICS, INC. KYMERA R&D DAY - December 16th, 2021 PAGE 97
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