1Q22 Investor Update

CANNABIST EXPANSION C Columbia Care's new retail storefront experience is centered on making shopping simple and approachable for the vast range of experience levels as cannabis use is normalized and legalized across the U.S., with knowledgeable staff and technology-enhanced interaction. 31 Cannabist Locations Open to Date Deptford, NJ Hermann, MO All 14 FL locations Virginia Beach, VA Williamstown, WV Beckley, WV Tempe, AZ • San Diego, CA Villa Park, IL Lowell, MA Springville, UT Boston, MA ● ● ● ● ● Near-term Pipeline 1 West Virginia location ● ● ● ● Brooklyn, NY • St. Albans, WV ● ● ● ● ● Morgantown, WV Chicago, IL Vineland, NJ Portsmouth, VA Early Insights - Cannabist Rebrand Impact Villa Park, IL Case Study(¹) +15% increase in revenue +19% increase in number of transactions Top 3 all-time highest weekly sales occurred since rebrand 1) Comparison of first 7 full weeks of operation as Cannabist to prior 7 weeks of operation prior to rebrand U CUM A Higher Experience 20

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