Q1 2023 Earnings Presentation

APPENDIX Q1 2023 GAAP Results Year-over-Year [$M, except EPS] Total Revenues Gross Profit Margin (% of revenue) SG&A (% of revenues) R&D (% of revenues) Operating Income (% of revenues) Net Income* EPS Diluted Shares Outstanding Q1 2023 685.3 359.7 52.5% (162.7) 23.7% (69.0) 10.1% 122.7 17.9% 76.5 $0.52 147.6 *Attributable to Bruker. Sum of items may not total due to rounding. 2023 Bruker Q1 2022 595.0 306.3 51.5% (145.7) 24.5% (56.6) 9.5% 96.5 16.2% 61.6 $0.41 151.4 A +15.2% +17.4% +11.7% +21.9% +27.2% +170 bps +24.2% +26.8% -2.5% Q1 2023 Earnings Presentation | BRUKER May 4, 2023 I 18

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