Avantor Results Presentation Deck

Reconciliations of GAAP to non-GAAP measures (continued) ($M) Debt, gross Less: cash and cash equivalents Numerator of adjusted net leverage TTM adjusted EBITDA TTM ongoing share-based compensation expense Pro forma adjustment for VWR Pro forma adjustment for projected synergies Denominator of adjusted net leverage Adjusted net leverage (non-GAAP) TTM adjusted EBITDA TTM covenant adjustments Pro forma adjustment for VWR Pro forma adjustment for projected synergies Denominator of covenant net leverage Covenant net leverage (non-GAAP) avantor™ 2017 7,396.1 (185.4) 7,210.7 289.5 21.6 472.6 783.7 9.2X 289.5 34.5 492.7 219.0 1,035.7 7.0X 2018 7,162.9 (184.7) 6,978.2 945.3 19.1 29.7 994.1 7.0X 945.3 60.7 145.1 1,151.1 6.1X 2019 5,249.4 (186.7) 5,062.7 1,031.2 31.1 26.8 1,089.1 4.6X 1,031.2 68.8 70.6 1,170.6 4.3X 2020 4,972.2 (286.6) 4,685.6 1,141.6 42.4 1.6 1,185.6 4.0x 1,141.6 91.0 (3.2) 1,229.4 3.8x 2021 Q1 4,702.0 (172.5) 4,529.5 1,241.9 43.7 1,285.6 3.5x 1,241.9 82.0 1,323.9 3.4x 17

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