Dare Bioscience Investor Presentation Deck
Contraception: What's Missing from Current Hormone-Free Options?
Pregnancies Expected
(per 100 women) ¹,*
T
Hormone-free Options
Spermicides
2
& Vaginal Gels ²
Condoms
(male)
Diaphragms
(with a spermicide)
Easy-to-use monthly
option
Copper IUD
>27
18
12
Effectiveness approaching
hormonal methods
<1
Least Effective
Most Effective
1.U.S. Food and Drug Administration Birth Control Guide dated 6/14/2021: https://www.fda.gov/consumers/free-publications-women/birth-control-chart
2.U.S. Food and Drug Administration Drug Data Prescribing information for a vaginal gel approved in 2020, PhexxiTM provides that in a multicenter, open-label, single-arm clinical trial in the U.S. (AMP002; NCT03243305), the 7-cycle cumulative pregnancy rate was 13.7% (95%
Cl: 10.0%, 17.5%), excluding cycles with back-up contraception, cycles <21 or > 35 days in length and cycles in which no intercourse was reported. The estimated Pearl Index, calculated based on data from the 7-cycle study, was 27.5 (95% CI: 22.4%, 33.596).
https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208352s0oolbl.pdf
* Pregnancy rates tell you the number of pregnancies expected per 100 women during the first year of typical use. Typical use shows how effective the different methods are during actual use (including sometimes using a method in a way that is not correct or not consistent).
For more information on the chance of getting pregnant while using a method or on the risks of a specific product, please check the product label or Trussell, J. (2011). "Contraceptive failure in the United States." Contraception 83(5):397-404.
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