23andMe Investor Presentation Deck

Strategic Sequencing Based on Polygenic Risk Scores Sequencing individuals from the tail ends of the polygenic risk score (PRS) distribution for whom the actual disease status does not match predictions low risk Polygenic Risk Score (PRS) Discovery of genes harboring rare variants of large effect high risk Copyright © 2024 23and Me, Inc. Legend: cases controls selected for sequencing 23andMe 37

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