Equillium Results Presentation Deck

A Differentiated Approach to Treating Lupus Nephritis A unique, upstream, disease modifying mechanism selectively targeting auto-reactive Teff cell activity and trafficking to promote immune homeostasis and induce durable disease remission Synergistic inhibition of multiple Teff cells and cytokines* equillium Teff Teff Teff Teff Inhibition of Teff trafficking into renal tissues Teff * including but not limited to IFN-y, TNF-a, IL-4, IL-5, IL-6, IL-13 and IL-17 CHO Restoration of immune regulation without broad immunosuppression Treg Teff 13

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