BioAtla Investor Presentation Deck
AXL expression is associated poor prognosis in metastatic NSCLC
Overall Survival (%)
100-
80-
60-
40-
0
bicatla
20
P=0.014 Low AXL
-High AXL
40
Months
60
80
In a cohort of 98 patients with metastatic NSCLC,
OS was significantly worse for those patients with
high AXL expression by IHC
Wu et al., J Cancer Res and Clin Oncol, 2017
Overall survival (%)
No. at risk
AXL low
AXL high
100-
80-
60-
40-
20-
0+
0
30
10
Median OS (95% CI), months
=
AXL low Undefined
AXL high = 19 (14.4-23.7)
10
29
9
20
30
Follow-up (months)
24
5
17
3
-AXL low
-AXL high
HR=8.51 (p=0.004)
40
10
1
50
00
Lower overall survival (OS) in patients with early
stage, surgically resected lung adenocarcinoma
with high levels of tissue AXL
Reproduced from de Miguel-Pérez D, et al. 2019
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