AstraZeneca Results Presentation Deck slide image

AstraZeneca Results Presentation Deck

Progress in the late-stage pipeline Milestones since the last results update Regulatory approval or other regulatory action Regulatory submission acceptance and/or submission Major Phase III data readout or other significant development Medicine Tagrisso Imfinzi Koselugo Lynparza Brilique Lynparza Farxiga roxadustat nirsevimab COVID-19 vaccine Indication (geography) adjuvant NSCLC¹ (EGFRm2): approval (CN) adjuvant NSCLC (EGFRm): positive opinion (EU) bladder cancer (2nd line³): indication voluntarily withdrawn (US) NF14: positive opinion (EU) breast cancer (BRCAm5): submission voluntarily withdrawn (CN) CAD/T2D7 CVOT8: submission voluntarily withdrawn (EU, CN) adjuvant breast cancer (BRCAm): Phase III primary endpoint met COVID-19: Phase III primary endpoint not met anaemia in CKDº: delay in regulatory decision due to convening of advisory committee (US) RSV10: Phase III primary endpoint met COVID-19: Phase III primary endpoint met (US trial) 1. Non-small cell lung cancer 2. Epidermal growth factor receptor mutation 3. 2nd treatment in the metastatic setting; 1st/2nd/3rd line used across this presentation 4. Neurofibromatosis type 1 5. Breast cancer susceptibility gene 1/2 mutation 6. Coronary artery disease 7. Type-2 diabetes 8. Cardiovascular outcomes trial 9. Chronic kidney disease 10. Respiratory syncytial virus. Status as of 30 April 2021. 7 4
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