BioNTech Investor Day Presentation Deck

Multi-platform innovation engine Expanding the therapeutic universe through platform extension and novel combinations TCR therapy Individualized TCR therapy Four drug classes Platforms Combination of platforms CAR-T Solid tumor CAR T cells Cell & gene therapies Individualized neoantigen T-cell therapy Off-the-shelf mRNA cancer vaccines Fix Vac CARVac mRNA-vaccine amplified CAR T cells mRNA-encoded humabodies (Crescendo) Individualized mRNA cancer vaccines iNeST mRNA technology RiboMabs mRNA-encoded multi-specific antibodies Ribolysins Precision antibacterials (Phagomed) Infectious diseases vaccines Prophylactic Therapeutic RiboCytokines mRNA-encoded cytokines Protein therapeutics Small molecules Targeted cancer therapies Next-gen immunomodulators Bispecific antibodies Selective TLR-7 agonism D F D 1 BIONTECH A 58

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