BenevolentAI Investor Conference Presentation Deck slide image

BenevolentAI Investor Conference Presentation Deck

Our prolific drug discovery engine drives higher productivity Number of new INDs filed by year by pharma and biotech companies. Median number of Phase I starts over five years (2015-2020)* Market cap¹ $211bn $288bn $281bn $263bn $122bn $140bn $108bn $0.5bn $18bn $74bn $79bn $29bn $1bn $5bn $0.5bn Companies with >20 commercialised products Companies with 3+ commercialised products Companies with <3 commercialised products AstraZeneca Pfizer Merck Roche sanofi AMGEN GILEAD Creating Possible Benevolent (Incyte) VERTEX REGENERON Alnylam sosel IONIS nektar Benevolent moderna DENALI Sangamo aclaris. EFFECTOR 1 2 2 2 N N 2 3 M 3 4 5 6 1-2 7 7 8 8 2-4 9 10 11 2027-31 AIM 2023-26 AIM 12 $0.5bn $69bn $4bn $1bn $1bn BenevolentAl potential productivity is in line with medium and large companies, but at a fraction of the total cost. BenevolentAl will aim to increase the number of INDS from its Platform with incremental cost largely from development through to the clinic only Note *IND filing rate is based on Phase I trial starts with the company as the lead sponsor. Average adjusted for companies which started clinical development during time period; ¹ Market cap as of 30/12/2022 (USD M) Source: clinicaltrials.gov; Company websites: L.E.K. research & analysis Benevolent 16
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