Ocuphire Pharma Results Presentation Deck
DRSS
10, 12
DR Absent
Step
Background on DRSS Assessment & Binocular DRSS
1
14
1
14, 15, 20
DR Questionable
2
2
35
Mild NPDR
3
3
Diabetic Retinopathy Severity Scale (DRSS)
43
Moderate NPDR
4
47 Moderately
Severe NPDR
5
5
53
Severe NPDR
6
6
60, 61
Mild PDR
7
65
Moderate PDR
8
8
71-75
High-risk PDR
9
81-85
Advanced PDR
Monocular calculation: Change in DRSS Step in a Single Eye (Study Eye or Fellow Eye)
Binocular calculation: Composite Change in DRSS Step in Study Eye and Change in DRSS Step in Fellow Eye
The ETDRS diabetic retinopathy severity scale (DRSS) is a categorical tool for clinical trials that contains 10 discreet steps from no retinopathy to severe proliferative retinopathy derived from the
grading of fundus photographs for each eye at a central reading center. Each patients' study eye had a baseline DRSS step of 5, 6 or 7 to be included in this trial.
10
10
OcuphireView entire presentation