23andMe Investor Day Presentation Deck slide image

23andMe Investor Day Presentation Deck

Example: Number of Osteoarthritis GWAS¹ hits dramatically increase as database grows 2016 2017 2021 log10(pvalue) - log10(pvalue) log10 (pvalue) 12- 10- 15 60 40- Size and Scale Accelerate Target Discovery 20 1 GWAS: Genome-Wide Association Study. 1 2 3 4 PT 5 ETSY 6 9 10 11 12 Chromosome 7 8 9 10 11 12 Chromosome 7 8 9 10 11 12 Chromosome 14 14 16 18 20 22 X 16 18 20 22 X 16 18 20 22 X Number of independent hits p<5e-8 New programs are identified through GWAS¹ hits, which increase as size of database grows 40,000 35,000 30,000 25,000 20,000 15,000 10,000 5,000 O 2015 2016 2017 2018 2019 Copyright © 2022 23andMe, Inc. 2020 23andMe® 26
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