ProSomnus SPAC Presentation Deck
Growing Library of Evidence Indicating ProSomnus's Performance
World Sleep Congress ¹
March 2022
Precision milled iterative
device and material
combination appear to yield
significantly better results to
previously demonstrated data
Journal of Dental Sleep
Medicine Abstract #0156
March 11-16
2022
MERICAN
ACADEMY OF
DENTAL
SLEEP
MEDICINE
WORLD
SLEEP
Rome• Italy
2020 Annual Meeting
~82% of patients, on average,
can be treated within 2
millimeters of the initial bite
position assuming the
standard of care protocol
1.
2.
3.
4.
5.
EFFECTS Study²
CUREUS
SCIENCE
V
JOURNAL
OF
EST. 2009
Ap
June 2021
Note: Tagline below study reflects key takeaways
Effective front-line therapy for
Mild/Moderate patients or
Severe who refuse CPAP
Sleep Science Study7
Sleep
Science
November 2020
Patients reported reduced
daytime sleepiness, reduced
snoring and improvements in
sleep indicating validity in the
oral appliance
SLEEP Journal, Vol. 44
Abstract # 434³
S
Kent Smith, et al. Efficacy of a Novel Precision Iterative Device and Material. World Sleep Conference. March 2022.
Stern J. Efficacy and Effectiveness of the ProSomnus® [IA] Sleep Device for the Treatment of Obstructive Sleep Apnea: EFFECTS Study. Cureus.
June 2021.
Sall E. Precision Oral Appliance Therapy: The Primetime Treatment for OSA. SLEEP Journal. Vol. 44, Abstract Supplement, 2021. Abstract #434.
Page A 172.
Elliott E, Ehtessabian J, Murphy M, Rein J, Seltzer N, Schwartz D, Shah S, Smith K. A Multi-Center Preference study of a Novel Oral Appliance
Design and Material for Better Provider, Physician, Patient and Payer Acceptance. SLEEP Journal. Vol. 44, Abstract Supplement, 2021. Abstract
# 440. Page A 174.
Murphy M, Munro K. Device Design's Impact on Dose in Oral Appliance Therapy. Journal of Dental Sleep Medicine. Vol. 8, No. 3 2021. Abstract
#004.
OXFORD
UNIVERSITY PRESS
Precision oral appliance is
capable of successfully treating
patients with all levels of
severity
2021 Annual Meeting
Sleep
Research
Society Ⓡ
Journal of Dental Sleep
Medicine
MERICAN
DENTAL
SLEEP
MEDICINE
Patients were highly satisfied
and devices had little effect on
tooth movement and bite
changes
6.
7.
2 Year Clinical Study
2019
8.
9.
OF
10.
Ⓡ
SLEEP Journal, Vol. 44
Abstract # 4404
S
Sleep
Research
Society
OXFORD
UNIVERSITY PRESS
2021 Annual Meeting
Patients preferred ProSomnus
EVO over CPAP and all other
devices similarly designed
Journal of Clinical Sleep
Medicine⁹
JCSM
- Journal of
Clinical Sleep
Medicine
2017 Annual Meeting
In-home feedback-controlled
mandibular positioning test
able to identify sufferers who
will respond to OAT and
provides efficacious position
Journal of Dental Sleep
Medicine Abstract #0045
PROSOMNUS
SLEEP TECHNOLOGIES
MERICAN
ACADEMY OF
DENTAL
SLEEP
MEDICINE
Patients of ProSomnus devices
are likely to experience fewer
side effects that could result in
discontinuation of treatment
Sall E. Minimization of Titration Protrusion for the Efficient Treatment of OSA. Journal of Dental Sleep Medicine. Vol. 7, No.2 2020. Abstract #015.
Kalha A. et al. Comparative assessment of changes in pharyngeal airway space in cases of obstructive sleep apnoea with a customized mandibular
repositioning appliance - a clinical study. Sleep Science. 2020; Ahead of Print.
Vranjes N. et al. Assessment of Potential Tooth Movement and Bite Changes With a Hard-Acrylic Sleep Appliance: A 2-Year Clinical Study. Journal
of Clinical Sleep Medicine. Vol. 6, No. 2 2019.
Remmers J. et al. A Feedback-Controlled Mandibular Positioner Identifies Individuals With SleepApnea Who Will Respond to Oral Appliance
Therapy. Journal of Clinical Sleep Medicine. Vol. 13, No. 7 2017.
2021 Virtual
Annual Meeting
Journal of Dental Sleep
Medicine ¹0
Charkhandeh S. et al. A Fully Digital Workflow and Device Manufacturing for Mandibular Repositioning Devices for the Treatment of Obstructive
Sleep Apnea: A Feasibility Study. Journal of Dental Sleep Medicine. Vol 4, No. 4 2017.
MERICAN
CADEMY OF
DENTAL
SLEEP
MEDICINE
R
It is feasible with predictable
outcomes, and patients prefer
devices from a fully digital
workflow
Feasibility Study
2017
19
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