AMD Results Presentation Deck

16 Q4 2021 SUMMARY P&L - GAAP ($ in millions, except per share data) Revenue Gross Profit Gross Margin % Operating Expenses Operating Expense/Revenue % Operating Income Operating Margin % Net Income ¹,2 Earnings Per Share 1,2,3 Q4 AND FY 2021 FINANCIAL RESULTS FEBRUARY 1, 2022 Q4'21 $4,826 $2,426 50% $1,223 25% $1,207 25% $974 $0.80 Q4'20 $3,244 $1,451 45% $881 27% $570 18% $1,781 $1.45 Y/Y Up 49% Up 67% Up 560bps Up 39% Down 2pp Up 112% Up 7pp Down 45% Down 45% Q3'21 $4,313 $2,086 48% $1,141 26% $948 22% $923 $0.75 Q/Q Up 12% Up 16% Up 190bps Up 7% Down 1pp Up 27% Up 3pp Up 6% Up 7% 1. Includes a higher tax rate beginning in Q1 2021 2. In Q4 2020, AMD released $1.3 billion of its $2.9 billion income tax valuation allowance. The valuation allowance release had a $1.06 benefit to Q4 2020 earnings per share. 3. See Appendices for share count reference. AMD

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