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argenx SE Investor Day Presentation Deck slide image

argenx SE Investor Day Presentation Deck

Efgartigimod Endogenous IgGs argenx 1 FcRn B2M Endogenous FcRn:IgG Interaction G Fc Fragment Binds to FcRn in Same Way as 2 Ulrichts et al, Clin Invest. 2018 tha Efgartigimod 3 P Efgartigimod binds to FcRn in the same formation as endogenous IgG Our hypothesis is that different binding properties of FcRn antagonists lead to different subcellular trafficking pathways Anti-FcRn mAb 18
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