Ginkgo Results Presentation Deck slide image

Ginkgo Results Presentation Deck

CASE STUDY 1 Ginkgo is developing 8 molecules for Cronos through two major programs, the first of which is expected to be commercialized this year CRONOS GROUP I ▪ Ginkgo Bioworks to design microorganisms which can produce desired "target cannabinoids" at an industrial scale ▪ 8 target cannabinoids to be produced by yeast via industrial fermentation ▪ Target production yields at a fraction of the cost of traditional cannabinoids production in plants: < $1,000 USD per KG Cronos Group will have the exclusive right to use and commercialize the key patented intellectual property related to the production of the target cannabinoids perpetually and globally CANNABINOID PRECURSORS NATURALLY OCCURRING IN PLANT DECARBOXYLATION Partnership Overview CBGA MAJOR CANNABINOIDS THCA CBDA CBCA Į THC Į ↓ CBD CBC CBGVA ✓ 1 THCVA CBDVA CBCVA Į THCV Program 1 Source: Cronos Group (FINAL Ginkgo Deal Announcement Presentation, September 4, 2018) ↓ CBDV Program 2 ↓ CBCV "At this stage, we have all the necessary licenses to commercialize a product using cultured cannabinoids produced in our Winnipeg facility and we plan to be the first to market with a product that leverages this technology in Canada later this year. We'll be using cultured CBG as our first product introduced to the market, enabled by our partnership with Ginkgo, and we expect the final productivity target for CBG will be achieved in the coming weeks prior to September 2021, as previously announced. We are making strides to ensure that Cronos become synonymous with innovation. Launching cultured rare cannabinoids as a broader long-term approach to branding and product differentiation." Partner (signed 2018) Program Goals Progress to Date Kurt Schmidt, President & CEO Cronos Q2 2021 Earnings Call (August 6, 2021) Collaboration in Brief Cronos Group, a publicly traded Canadian cannabis company Design microorganisms that can produce desired target cannabinoids through industrial-scale fermentation Cronos has announced commercial production and upcoming market launch of CBG (first of 8 molecules) H1 UPDATE | AUGUST 2021 GINKGO BIOWORKS 17
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