Certara Investor Day Presentation Deck

Mechanistic biosimulation is used to quantitatively predict, without human or animal studies... What you want the drug to do to the body Quantitative systems Pharmacology (QSP) Simcyp QSP What the body does to the drug Physiologically-based pharmacokinetics (PBPK) Simcyp Simulator What you don't want the drug to do to the body Quantitative systems toxicology and safety (QSTS) Secondary Intelligence Primary Target Off Target Interactions Secondary Effects Adapted from Jenkinson et al., 2020 33 CERTARA

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