Immix Biopharma Investor Presentation Deck
Only CAR-T in BCMA-exposed multiple myeloma,
a rapidly growing patient segment (1/2)
Representative
Treatment
Results
Representative
patient number
growth
Newly diagnosed
Bortezomib, lenalidomide, and
(VRD) is stand
dex
therapy for newly diagnosed multiple
myeloma
-50% relapse at month 30
Standard-of-care refractory
BCMA-targeted antibodies
(Tecvayli-J&J; Elrexfio-Pfizer)
bispecifics
-50% relapse at month 11-15
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IMMIX
S BIOPHARMA
BCMA-exposed,
a rapidly growing patient segment
Limited treatment options (no approved treatments)
NXC-201:
75% overall response rate; 50% complete
response rate
"Recent studies of anti-BCMA BsAbs, ... demonstrate that patients may experience disease progression after treatment, leaving them with few other treatment options." Cohen et al, Blood, 2023
Source: https://doi.org/10.1038/s41591-023-02528-9 Nature Medicine, Lancet Oncol. 2020 October; 21(10): 1317-1330. doi:10.1016/S1470-2045(20)30452-6, ; Teclistamab in Relapsed or Refractory Multiple Myeloma New England Journal of Medicine Aug 11 2022. Figures reflect
cross-trial comparison and not results from a head-to head study. Differences exist between trial designs and subject characteristics, and caution should be exercised when comparing data across studies. Cohen et al 2023 https://doi.org/10.1182/blood.2022015526
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