OmniAb Investor Presentation Deck

Rodent Platforms ● ● ● Endogenous lg genes inactivated Expression of full human V gene diversity Streamlined conversion into fully human molecule Well-validated transgene design utilizes rodent constant regions for robust immune responses from the B-cell repertoire Geurts et al. Science 2009 Ménoret et al. Eur J Immunol 2010 Osborn et al. J. Immunol. 2013 VL Light chain loci CL Fully human LC VJ C mRNA ţ OmniRat* mniMouse + ОЮП VDJ C VH Heavy chain locus DH JH EuCuCy1 Cy2b εα HHHHH▬▬▬▬▬▬▬ Rat constant Human V, D, J Easy conversion Human Antibody 15 OmniAb

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