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argenx SE Investor Day Presentation Deck slide image

argenx SE Investor Day Presentation Deck

ARGX-117 Blocks and Actively Removes C2 from Circulation Features of ARGX-117 pH and Ca2+ switch No effector function argenx Optimal recycling 2 Uptake & drop off C2 FcRn ARGX-117 C2 Sweeping Antibody 1 pH: 7.4 Ca²+: 1.5 mM 1 Cell 3 Bind & block C2 3 Endosome *********** Lysosome Degradation of C2 4 Recycling of ARGX-117 55
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