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Investor Presentation

Second Quarter 2021 Financial Highlights O Record Quarterly Revenue - Strong Base, COVID tailwinds ā—‹ $163M; +86% overall, +69% organic I. BASE: 31 pts. of growth II. COVID: 42 pts. of growth III. M&A: 13 pts. of growth Gross Margin and Operating Margin Expansion o GAAP GM: 62% (from 57.9% Q2 '20) o Adjusted GM: 62% (from 58.2% Q2 '20) o GAAP Op. Margin: 29.6% (from 22.3% Q2 '20) o Adjusted Op. Margin: 34.7% Adjusted (from 29.2% Q2 '20) Net Income Per Share (EPS) Growth o Fully diluted EPS: $0.64 GAAP (from $0.30 Q2 '20) o Adjusted Fully diluted EPS $0.79 (from $0.42 Q2 '20) M&A, 7% $0.90 $0.80 $0.70 $0.60 $0.50 $0.40 $0.30 $0.20 $0.10 $0.00 BASE, 66% $0.42 Q2 '20 RREPLIGEN INSPIRING ADVANCES IN BIOPROCESSING COVID, 27% $0.79 Q2 '21 Q2 2021 Revenue Composition Q2 2021 Adj. EPS 20
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