Genelux Investor Presentation Deck slide image

Genelux Investor Presentation Deck

The Most Advanced Non-local Delivery Oncolytic Immunotherapy Olvi-Vec: Engineered to selectively target and eliminate tumor cells while inducing a robust patient-specific immune response ■ Physician-preferred Routes of Delivery Regional and systemic administration to preferentially locate, colonize and destroy tumor cells In Ovarian Cancer trials, catheter placement is prior to chemotherapy, with removal 2 days after initial placement. IV therapy currently being used in small cell lung cancer Phase 1 trial. GENELUX Antitumor Effect and Well Tolerated Strong data in Phase 1b/2 study in platinum-resistant/refractory ovarian cancer (PRROC) No Maximum Tolerated Dose (MTD) observed+ Potential utility in multiple cancers (demonstrated in 20 pre-clinical tumor models), including metastatic disease Rey Ideal Backbone of Combination Therapy Turns tumors "hot" by localized inflammation and induction of the influx of tumor infiltrating lymphocytes (TILs) Positively modulates anti-tumor pathways in tumor microenvironment 4
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