ProSomnus SPAC Presentation Deck slide image

ProSomnus SPAC Presentation Deck

Low Adherence Limits Effectiveness of CPAP Therapy CPAP is the current leading therapy for OSA, but inherent design flaws and patient-experience drawbacks mean adherence (hours worn) has barely changed in 20 years CPAP MANUFACTURERS X X X REASONS FOR CPAP NON-ADHERENCE X X ResMed X PHILIPS RESPIRONICS Fisher&Paykel HEALTHCARE Mask discomfort Mask leakage Claustrophobia Pressure intolerance Skin irritation Noise from bedside pump X Nasal congestion X X X X Nosebleeds Nasal drying Inconvenience of device / consumables maintenance Lack of intimacy, partner disturbance, social issues X Limited portability CPAP ADHERENCE - HOURS WORN¹,2,3 3.9 Hours Despite significant investment and innovation, CPAP adherence has barely changed in 20 years ProSomnus devices demonstrated 60.7%ª better mean nightly use in clinical studies CPAP: 1999 1. Rotenberg BW, Murariu D, Pang KP. Trends in CPAP adherence over twenty years of data collection: a flattened curve. J Otolaryngol Head Neck Surg. 2016 Aug 19 2. Dieltjens M, Vanderveken O. Oral Appliances in Obstructive Sleep Apnea. Healthcare (Basel). 2019 Nov 8 3. Stern, J. Efficacy and Effectiveness. Annual Meeting of the AADSM, 2018 Jun 4. Calculated as % increase from 4.5 hours to 7.2 hours 60.7% O 4.5 Hours PROSOMNUS SLEEP TECHNOLOGIES CPAP: 2019 7.2 Hours ProSomnus 29 STRICTLY CONFIDENTIAL
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