BioAtla Investor Presentation Deck
Phase 1 results with BA3021 support advancing into Phase 2
in multiple indications
ROR2+ Tumor Types
NSCLC
Melanoma
SCCHN
bicatla
Results
▪ PR in 2/3 patients who previously experienced failure on PD-1 and who
received Ph2 dose or higher
CR in 1 / 1 patient who previously experienced failure on PD-1
Clearance of pulmonary metastases followed by normalization of adenopathy
■ Continued CR off treatment for over 2 years
.
▪ PR in 1/1 ROR2+ refractory to four prior lines of therapy including cetuximab
and PD-1 (pembrolizumab)
Promising safety and tolerability profile across multiple tumor types
No ROR2 ADC or small molecules in the clinic to date, suggesting CAB-ROR2-ADC is a first-in-class
therapy across multiple tumor types
BioAtla| Overview 27View entire presentation