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SeaSpine Investor Update

$250.0 $200.0 $150.0 $100.0 $50.0 FINANCIAL HIGHLIGHTS Accelerating Revenue Growth 2015 -3% 2016 2% 2017 Total Revenue ($ in millions) 9% 2018 Total Revenue 11% 2019 Revenue Growth n -3% Ⓒ2022 SeaSpine Orthopedics Corporation. All rights reserved | 23 2020 2022 represents the mid-point of FY 2022 revenue guidance of $234-$236M. 24% 2021 22% 2022 30% 25% 20% 15% 10% 5% 0% -5% -10% SeaSpine
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