23andMe Investor Presentation Deck

Health Predispositions 30+ Including: Type 2 Diabetes (Powered by 23andMe Research) Coronary Artery Disease 23andMe+ Uterine Fibroids Migraine 23 and Me+ MUTYH-Associated Polyposis BRCA1/BRCA2 (selected variants) HOXB13 (prostate cancer) Type 2 Diabetes YOUR RESULT Your genetics are associated with a typical likelihood. Based on your DD Genetics Age Our Health Service The First and Only Multi-Disease DTC Genetic Service That Includes FDA-Authorized Reports and Provides Personalized Genetic Insights and Tools 37% H Ethnicity 1 Wellness information does not require FDA Authorization. Wellness¹ 10 Including: Muscle Composition Genetic Weight Alcohol Flush Reaction Saturated Fat and Weight Sleep Movement Dog & Cat Allergies 23andMe+ Genetic Weight YOUR RESULT Your genes predispose you to weigh about 7% less than average. Average 142 lbs Carrier Status 40+ Including: Cystic Fibrosis Sickle Cell Anemia Familial Hyperinsulinism (ABCC8-Related) Tay-Sachs Disease Glycogen Storage Disease (Type 1a) Chromosome 15 Tay-Sachs Disease YOUR RESULT You do not have the variants we tested. (1) 0 variants detected in the HEXA gene Pharmacogenetics 3 Including: SLC01B1 Drug Transport CYP2C19 Drug Metabolism DPYD₂ Drug Metabolism e.g., citalopram and clopidogrel Copyright © 2022 23and Me, Inc. Pharmacogenetics Genetic variants may influence how you process medications. YOUR RESULTS CYP2C19 Drug Metabolism LIKELY NORMAL METABOLIZER DPYD Drug Metabolism LIKELY NORMAL METABOLIZER SLCO1B1 Drug Transport LIKELY NORMAL METABOLIZER 7 FDA Authorizations Print summary 23andMe+ 23andMe 15

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