BenevolentAI SPAC Presentation Deck
Identified a now FDA-approved
reduces mortality by 38%
COVID-19 Drug Identification Custom Workflow
Human-guided iterative queries of Knowledge Graph
Computational tools enabled scientists to explore the information in
the graph. Identified a number of suitable approved drugs through
interactive and visual presentations of data
Identified baricitinib - an approved rheumatoid arthritis drug -
as the strongest candidate in just 48 hours
Uncovered previously unknown anti-viral properties
Our technology was able to extract and infer new scientific
information about baricitinib's combined anti-viral and anti
inflammatory mechanism of action
Research published in Feb 2020 in THE LANCET &
ECMO - extracorporeal membrane oxygenation
THE LANCET
Infectious Diseases
COVID-19 treatment that
Lilly
Eli Lilly owns baricitinib. Relationship developed into
equity investment in Q4 2020 funding round
✔ NOVEL
Our tech identified a novel antiviral mechanism from
published research data using our proprietary NLP and
engineering frameworks
✔ RAPID
BenevolentAl introspection tools empowered scientists to
rapidly explore and evaluate possible biological narratives &
access hypotheses in just 48 hrs
✓ EFFECTIVE
Baricitinib is the most effective treatment proven to reduce
mortality from COVID-19 in randomised Control Trials:
COV-BARRIER trial showed baricitinib reduces mortality
by 38% across all patients, and by 46% in ventilated or
ECMO patients
✔WORLD-FIRST
Of 81 studies using Al to predict drugs to treat COVID-19,
ours is the only one to be clinically approved. Now
approved as a treatment in the US, Japan & India
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