AMD Results Presentation Deck

20 1. Revenue 2. FINANCIAL OUTLOOK - NON-GAAP Q1 2022 ~$5.0 Billion +/- $100 Million ~50.5% Gross Margin % Operating Expenses Operating Expenses/Revenue % Interest Expense, Taxes and Other Effective Tax Rate Cash Tax Rate Diluted Share Count² Note: Guidance does not contemplate the addition of Xilinx as the transaction has not yet closed. See Cautionary Statement on Slide 2. These forward-looking outlook statements and non-GAAP measures are based on current expectations as of February 1, 2022, and assumptions and beliefs that involve numerous risks and uncertainties. AMD undertakes no intent or obligation to publicly update or revise its outlook statements as a result of new information, future events or otherwise, except as may be required by law. All items, except revenue, are on a non-GAAP basis. Adjustments to arrive at the GAAP financial outlook typically include stock-based compensation, non-cash interest expense related to convertible debt, income tax provision, equity income in investee, and other non-recurring items such as loss on debt redemption/conversion, impairment charges and acquisition-related costs. The timing and impact of such adjustments are dependent on future events that are typically uncertain or outside of AMD's control; therefore, a reconciliation to equivalent GAAP measures is not practicable at this time. Refer to Diluted Share Count overview in the Appendices Q4 AND FY 2021 FINANCIAL RESULTS | FEBRUARY 1, 2022 ~$1.2 Billion ~24% ~$207 Million 1 FY 2022 -$21.5 Billion Growth of ~31% y/y ~51% ~24% ~15% of pre-tax income ~9% of pre-tax income ~1.22 billion shares AMD

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