Avantor Results Presentation Deck

3 Regional Core Organic Growth & Adjusted EBITDA (Quarterly) USD in millions Americas GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales growth Adjusted EBITDA (non-GAAP) Adjusted EBITDA margin Adjusted EBITDA margin growth (-bps) Europe GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales growth Adjusted EBITDA (non-GAAP) Adjusted EBITDA margin Adjusted EBITDA margin growth (~bps) AMEA GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales growth Adjusted EBITDA (non-GAAP) Adjusted EBITDA margin Adjusted EBITDA margin growth (-bps) avantor™ $ $81 (19) $62 47 (1) $108 $ $41 (24) $17 52 (40) $30 $ $9 3 $12 18 (3) $27 1Q22 $1,143 $294 25.7% 140 bps % 7.8% -1.8% 6.0% 4.6% -0.1% 10.5% 1Q22 $680 % 6.3% -3.7% 2.6% 8.1% -6.1% 4.6% $143 21.1% 90 bps 1Q22 $127 % 8.6% 3.1% 11.7% 17.7% -2.8% 26.6% $29 23.1% 50 bps $ $87 (42) $45 45 (4) $87 $ $31 (33) ($2) 31 2Q22 $1,157 $290 25.1% 160 bps (71) ($42) $ ($0) (1) ($2) 15 (6) $7 % 8.1% -3.8% 4.3% 4.2% -0.4% 8.1% 2Q22 $624 % 4.7% -4.9% -0.2% 4.6% -10.7% -6.3% $119 19.1% 50 bps 2Q22 $130 % -0.3% -1.0% -1.3% 11.8% -4.6% 5.9% $36 27.7% 450 bps $ $92 (40) $52 31 (4) $78 3Q22 $1,123 $ $17 7 $24 9 (9) $24 % 8.8% -3.9% 4.9% 2.9% -0.3% 7.5% $262 23.4% 80 bps $ $32 (26) $7 7 (93) ($80) 3Q22 $595 % 4.8% -3.8% 1.0% 1.1% -13.9% -11.8% $130 21.9% 180 bps 3Q22 $138 % 15.1% 5.7% 20.8% 7.8% -8.0% 20.6% $36 25.8% 10 bps 4Q22 $1,048 $ % $1 0.1% (45) -4.1% ($44) -4.1% 10 0.9% (5) ($39) -0.5% -3.6% $231 22.0% 10 bps $ $8 (5) $3 2 (9) ($4) 4Q22 $617 $ $43 (42) $1 2 (72) ($69) % 6.3% -6.1% 0.2% 0.3% -10.5% -10.1% $131 21.2% -40 bps 4Q22 $130 % 5.7% -3.5% 2.2% 1.5% -6.7% -3.1% $40 31.1% 620 bps 1Q23 $1,032 $ ($43) (65) ($108) 0 (4) ($111) $240 23.3% -240 bps % -3.7% -5.7% -9.4% 0.0% -0.3% -9.7% $ $7 (24) ($17) 0 (33) ($50) $ $1 (4) ($3) 0 (6) ($9) 1Q23 $630 % 1.0% -3.6% -2.6% 0.0% -4.8% -7.4% $122 19.3% -180 bps 1Q23 $118 % 1.0% -3.3% -2.3% 0.0% -4.4% -6.7% $34 28.4% 530 bps Note: the sum of Americas, Europe, and AMEA does not equal Total, Avantor. Does not include corporate-level expenses 2Q23 $1,026 $ ($102) (28) ($130) 0 (1) ($131) $247 24.1% -95 bps $ ($11) (17) ($28) 0 11 ($17) % -8.8% -2.4% -11.2% 0.0% -0.1% -11.3% $ ($11) (5) ($16) 0 (2) ($19) 2Q23 $607 $111 18.3% -80 bps % -1.8% -2.7% -4.5% 0.0% 1.8% -2.7% 2Q23 $111 % -8.7% -3.9% -12.6% 0.0% -1.8% -14.4% $26 23.7% -405 bps 6

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