Certara Investor Presentation Deck slide image

Certara Investor Presentation Deck

Long history of innovation driven by investment in our platform I 10 new software applications i | and updates in 2021 1 Regulatory Milestones Product Innovation FDA CRADA for veterinary drug development Phoenix v1.3 2012 Sim CYP Drug comes off FDA safety hold using biosim. Simcyp Cardiac Safety Simulator 2013 I I © Copyright 2022 Certara, Inc. All rights reserved. I I Great Lakes Brug Development, Inc. "Bridging the Gap in Drug Development" ● ● FDA grant for Simcyp dermal model Orphan drug DDI study waived using biosim. Launch of Pre-clinical Safety Store 2014 synchrogenix formulation approval isolely using PBPK I Alt. I | Virtual monkey for in silico animal testing 2015 ClinGenuity G Quantitative Solutions XenologiQ I I FDA grant for supersaturat ing drugs Phoenix PK/PD CoEs in China and Japan 2016 I I | First gene I I I I therapy eCTD submission • First immuno- genicity QSP consortium ● 2017 I d3 MEDICINE Global Submit GlobalSubmit I Two FDA grants for virtual bioequivalence i • D360 I Reg. mechanistic ! • First immuno- modeling oncology QSP workshops incorporating biologics I I consortium 2018 ! First FDA i complex i generic virtual i bioequiv. approval BASECASE LASER ANALYTICA I PIRANA Certara Integral Data Repository 2019 I ! Acne drug I approval without i pediatric testing I I Covidpharma- I cology.com launch ! Launched Version 25+ COVID-19 programs 2020 ! Majority of new i FDA drug I i approvals used our I end-to-end platform YTD ISB 200 19 i I I I I IN SILICO BIOSCIENCES 21 of Simcyp PBPK Simulator author Well-positioned to continue delivering growth through organic and inorganic opportunities 2021 MEDICAL WRITING Insight PINNACLE²¹ CERTARA
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